Voluntary Initiatives

Voluntary Initiatives

As well as legal requirements for chemical safety assessment, there are also voluntary initiatives for the examination of the impacts of chemical products on health and the environment.

The High Production Volume Chemicals Programme (HPVC) is an international programme which assesses the potential hazard of chemicals produced or imported at more than 1,000 tonnes per year. The programme is run by the Organisation for Economic Co-operation and Development (OECD) and supported by the International Council of Chemical Associations (ICCA). The US has a similar HPV Challenge Programme.

HPVC involves the production of a dossier reviewing the available data and a report (SIDS Initial Assessment Report or SIAR) that brings the data together and draws conclusions for the environment and human health.

PFA can provide the following package of services, to support companies or consortia making a submission into the HPV process:

  • collation and review of study reports
  • collation of published data from the open literature
  • data gap filling, e.g. using QSAR techniques
  • preparation of robust summaries in the IUCLID program
  • addition of other key data to complete the SIDS* Dossier
  • category justification (if appropriate)
  • SIDS Initial Assessment Report (SIAR)
  • SIDS Initial Assessment Profile (SIAP)
  • liaison with Competent Authorities and the OECD discussion forum (and CoCAM), as appropriate