Substitution

Substitution

Chemicals that are successful in the market do well because they have properties that are useful, at an acceptable price. Their hazards and risks, where known, need to be acceptable too.

Sometimes risk assessment and socio-economic analysis may reveal that the best option is to substitute a particular chemical for another. Legislation such as the REACH Regulation and the Carcinogens Directive necessitate detailed consideration of the replacement of the most hazardous substances with more acceptable alternatives. Even if there are no regulatory pressures to substitute, there are economic benefits to the substitution of hazardous substances for ‘green’ alternatives.

A variety of tools exists to support decision making in industry in relation to possible substitution of chemicals. A thorough understanding of the relationship between chemical structure and properties, and use of predictive methods and models, allows scientists to consider the theoretical environmental impact of a particular candidate chemical in a given application, at the very earliest stages of development.

PFA’s background in product chemistry and the fate and effects of chemical substances, and work spanning industry, regulators and academics, has allowed the building of a service that can offer real and practical help on substitution.  This service is directed at manufacturers and users of chemicals that are seeking to enhance their product portfolios and optimise and secure their customer bases with safer and more acceptable products.