Exposure

Exposure training modules

The teaching material on the exposure side of chemical safety assessment is based on expert knowledge in gathering and processing information on human health and environmental exposure. Based on years of experience, PFA is able to provide interactive and practical training on the most up to date models used to derive Predicted Environmental Concentrations (PECs) and human exposure levels, Risk Characterisation Ratios (RCRs) and how to deal with unacceptable risks.

How to find good information about exposure to chemicals

This course does not cover the basic models, but gives a detailed guide on how to move beyond standard models to industry-specific scenarios.

Human exposure to chemicals - basics

Basic (Tier 1) models for qualitative and quantitative exposure of workers, professional and consumers are described and demonstrated. The basis for deriving exposure concentrations is explained.

Human exposure to chemicals - advanced

The weaknesses of Tier 1 models are discussed, and higher Tier models introduced, explained and exemplified. However, more complex models may not always improve exposure assessment. A critical discussion of available models is provided.

Basic risk characterisation - health

What data are required to conduct a risk characterisation? How do we gather the information and how does it translate into human health risk characterisation? The data requirements are explained and available models for conducting the assessment are presented.

Advanced risk characterisation - health

The approaches used to calculate Derived No-Effect Levels (DNELs) are reviewed, along with higher Tier exposure models. If risks are unacceptable, what are the next steps? Can monitoring help? Is a higher level of control the only solution?

Environmental exposure to chemicals - basics

Manufacturers and downstream users often believe that their substance cannot be reaching the environment. However, regulators will not accept such a claim without concrete proof. The basis to understanding chemical releases to the environment is explored.

Environmental exposure to chemicals - advanced

The releases of chemicals into the environment from less obvious sources are described in this module. The modelling of Predicted Environmental Concentrations (PECs) is discussed in detail.

Basic risk characterisation - environment

What data are required? How do we gather the information and how does it translate into environmental risk characterisation? The data requirements are explained and available models for conducting the assessment are presented.

Advanced risk characterisation - environment

The emphasis of this module is on problem solving following the identification of risks. Should the focus be on properties, releases, monitoring, or a combination of the above? This module is recommended in conjunction with the advanced module on ‘Environmental exposure to chemicals’.